Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells

BACKGROUND: To elucidate whether rapamycin, the inhibitor of mTOR (mammalian target of rapamycin), can potentiate the cytotoxic effect of docetaxel in lung cancer cells and to probe the mechanism underlying such enhancement. METHODS: Lung cancer cells were treated with docetaxel and rapamycin. The e...

Descripción completa

Detalles Bibliográficos
Autores principales: Niu, Huiyan, Wang, Jiahe, Li, Hui, He, Ping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065416/
https://www.ncbi.nlm.nih.gov/pubmed/21392382
http://dx.doi.org/10.1186/1756-9966-30-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065416/
https://www.ncbi.nlm.nih.gov/pubmed/21392382
http://dx.doi.org/10.1186/1756-9966-30-28

Ejemplares similares