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Serum response factor is required for cell contact maintenance but dispensable for proliferation in visceral yolk sac endothelium

BACKGROUND: Endothelial-specific knockout of the transcription factor serum response factor (SRF) results in embryonic lethality by mid-gestation. The associated phenotype exhibits vascular failure in embryos as well as visceral yolk sac (VYS) tissues. Previous data suggest that this vascular failur...

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Detalles Bibliográficos
Autores principales: Holtz, Mary L, Misra, Ravi P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065428/
https://www.ncbi.nlm.nih.gov/pubmed/21401944
http://dx.doi.org/10.1186/1471-213X-11-18