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Location of Immunization and Interferon-γ Are Central to Induction of Salivary Gland Dysfunction in Ro60 Peptide Immunized Model of Sjögren's Syndrome

INTRODUCTION: Anti-Ro antibodies can be found in the serum of the majority of patients with Sjögren's syndrome (SS). Immunization with a 60-kDa Ro peptide has been shown to induce SS-like symptoms in mice. The aim of this study was to investigate factors involved in salivary gland (SG) dysfunct...

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Detalles Bibliográficos
Autores principales: Yin, Hongen, Vosters, Jelle L., Roescher, Nienke, D'Souza, Anil, Kurien, Biji T., Tak, Paul P., Chiorini, John A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065457/
https://www.ncbi.nlm.nih.gov/pubmed/21464925
http://dx.doi.org/10.1371/journal.pone.0018003