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Selective Attenuation of Norepinephrine Release and Stress-Induced Heart Rate Increase by Partial Adenosine A(1) Agonism

The release of the neurotransmitter norepinephrine (NE) is modulated by presynaptic adenosine receptors. In the present study we investigated the effect of a partial activation of this feedback mechanism. We hypothesized that partial agonism would have differential effects on NE release in isolated...

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Detalles Bibliográficos
Autores principales: Bott-Flügel, Lorenz, Bernshausen, Alexandra, Schneider, Heike, Luppa, Peter, Zimmermann, Katja, Albrecht-Küpper, Barbara, Kast, Raimund, Laugwitz, Karl-Ludwig, Ehmke, Heimo, Knorr, Andreas, Seyfarth, Melchior
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065468/
https://www.ncbi.nlm.nih.gov/pubmed/21464936
http://dx.doi.org/10.1371/journal.pone.0018048