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Conditioned Pain Modulation Is Associated with Common Polymorphisms in the Serotonin Transporter Gene

BACKGROUND: Variation in the serotonin transporter (5-HTT) gene (SLC6A4) has been shown to influence a wide range of affective processes. Low 5-HTT gene-expression has also been suggested to increase the risk of chronic pain. Conditioned pain modulation (CPM) - i.e. ‘pain inhibits pain’ - is impaire...

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Detalles Bibliográficos
Autores principales: Lindstedt, Fredrik, Berrebi, Jonathan, Greayer, Erik, Lonsdorf, Tina B., Schalling, Martin, Ingvar, Martin, Kosek, Eva
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065474/
https://www.ncbi.nlm.nih.gov/pubmed/21464942
http://dx.doi.org/10.1371/journal.pone.0018252