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Plerixafor for autologous CD34(+) cell mobilization
High-dose chemotherapy and autologous transplantation of hematopoietic cells is a crucial treatment option for hematologic malignancy patients. Current mobilization regimes often do not provide adequate numbers of CD34(+) cells. The chemokine receptor CXCR4 and ligand SDF-1 are integrally involved i...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065558/ https://www.ncbi.nlm.nih.gov/pubmed/21468240 http://dx.doi.org/10.2147/CE.S7801 |