The Impact of Dosing Interval in a Novel Tandem Oral Dosing Strategy: Enhancing the Exposure of Low Solubility Drug Candidates in a Preclinical Setting

In drug discovery, time and resource constraints necessitate increasingly early decision making to accelerate or stop preclinical programs. Early discovery drug candidates may be potent inhibitors of new targets, but all too often exhibit poor pharmaceutical or pharmacokinetic properties that limit...

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Detalles Bibliográficos
Autores principales: Chiang, Po-Chang, South, Sarah A., Wene, Steve P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065744/
https://www.ncbi.nlm.nih.gov/pubmed/21490753
http://dx.doi.org/10.1155/2011/528284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065744/
https://www.ncbi.nlm.nih.gov/pubmed/21490753
http://dx.doi.org/10.1155/2011/528284

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