Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells

BACKGROUND: Gene therapy is a potentially effective therapeutic modality for treating sensorineural hearing loss. Nonviral gene delivery vectors are expected to become extremely safe and convenient, and nanoparticles are the most promising types of vectors. However, infrequent nuclear localization i...

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Detalles Bibliográficos
Autores principales: Zhang, Weikai, Zhang, Ya, Löbler, Marian, Schmitz, Klaus-Peter, Ahmad, Aqeel, Pyykkö, Ilmari, Zou, Jing
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065799/
https://www.ncbi.nlm.nih.gov/pubmed/21468356
http://dx.doi.org/10.2147/IJN.S16973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065799/
https://www.ncbi.nlm.nih.gov/pubmed/21468356
http://dx.doi.org/10.2147/IJN.S16973

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