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Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells
BACKGROUND: Gene therapy is a potentially effective therapeutic modality for treating sensorineural hearing loss. Nonviral gene delivery vectors are expected to become extremely safe and convenient, and nanoparticles are the most promising types of vectors. However, infrequent nuclear localization i...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065799/ https://www.ncbi.nlm.nih.gov/pubmed/21468356 http://dx.doi.org/10.2147/IJN.S16973 |