A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors

Cys-loop receptors (CLR) are pentameric ligand-gated ion channels that mediate fast excitatory or inhibitory transmission in the nervous system. Strychnine and d-tubocurarine (d-TC) are neurotoxins that have been highly instrumental in decades of research on glycine receptors (GlyR) and nicotinic ac...

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Detalles Bibliográficos
Autores principales: Brams, Marijke, Pandya, Anshul, Kuzmin, Dmitry, van Elk, René, Krijnen, Liz, Yakel, Jerrel L., Tsetlin, Victor, Smit, August B., Ulens, Chris
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066128/
https://www.ncbi.nlm.nih.gov/pubmed/21468359
http://dx.doi.org/10.1371/journal.pbio.1001034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066128/
https://www.ncbi.nlm.nih.gov/pubmed/21468359
http://dx.doi.org/10.1371/journal.pbio.1001034

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