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Enzymatic Shaving of the Tegument Surface of Live Schistosomes for Proteomic Analysis: A Rational Approach to Select Vaccine Candidates

BACKGROUND: The membrane-associated and membrane-spanning constituents of the Schistosoma mansoni tegument surface, the parasite's principal interface with the host bloodstream, have recently been characterized using proteomic techniques. Biotinylation of live worms using membrane-impermeant pr...

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Detalles Bibliográficos
Autores principales: Castro-Borges, William, Dowle, Adam, Curwen, Rachel S., Thomas-Oates, Jane, Wilson, R. Alan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066142/
https://www.ncbi.nlm.nih.gov/pubmed/21468311
http://dx.doi.org/10.1371/journal.pntd.0000993