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Effects of Transmitters and Amyloid-Beta Peptide on Calcium Signals in Rat Cortical Astrocytes: Fura-2AM Measurements and Stochastic Model Simulations

BACKGROUND: To better understand the complex molecular level interactions seen in the pathogenesis of Alzheimer's disease, the results of the wet-lab and clinical studies can be complemented by mathematical models. Astrocytes are known to become reactive in Alzheimer's disease and their io...

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Detalles Bibliográficos
Autores principales: Toivari, Eeva, Manninen, Tiina, Nahata, Amit K., Jalonen, Tuula O., Linne, Marja-Leena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066169/
https://www.ncbi.nlm.nih.gov/pubmed/21483471
http://dx.doi.org/10.1371/journal.pone.0017914