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Effects of Transmitters and Amyloid-Beta Peptide on Calcium Signals in Rat Cortical Astrocytes: Fura-2AM Measurements and Stochastic Model Simulations
BACKGROUND: To better understand the complex molecular level interactions seen in the pathogenesis of Alzheimer's disease, the results of the wet-lab and clinical studies can be complemented by mathematical models. Astrocytes are known to become reactive in Alzheimer's disease and their io...
Autores principales: | Toivari, Eeva, Manninen, Tiina, Nahata, Amit K., Jalonen, Tuula O., Linne, Marja-Leena |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066169/ https://www.ncbi.nlm.nih.gov/pubmed/21483471 http://dx.doi.org/10.1371/journal.pone.0017914 |
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