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A Mutation in Myo15 Leads to Usher-Like Symptoms in LEW/Ztm-ci2 Rats

The LEW/Ztm-ci2 rat is an animal model for syndromal deafness that arose from a spontaneous mutation. Homozygous animals show locomotor abnormalities like lateralized circling behavior. Additionally, an impaired vision can be observed in some animals through behavioral studies. Syndromal deafness as...

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Detalles Bibliográficos
Autores principales: Held, Nadine, Smits, Bart M. G., Gockeln, Roland, Schubert, Stephanie, Nave, Heike, Northrup, Emily, Cuppen, Edwin, Hedrich, Hans J., Wedekind, Dirk
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066203/
https://www.ncbi.nlm.nih.gov/pubmed/21479269
http://dx.doi.org/10.1371/journal.pone.0015669