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A Mutation in Myo15 Leads to Usher-Like Symptoms in LEW/Ztm-ci2 Rats
The LEW/Ztm-ci2 rat is an animal model for syndromal deafness that arose from a spontaneous mutation. Homozygous animals show locomotor abnormalities like lateralized circling behavior. Additionally, an impaired vision can be observed in some animals through behavioral studies. Syndromal deafness as...
Autores principales: | Held, Nadine, Smits, Bart M. G., Gockeln, Roland, Schubert, Stephanie, Nave, Heike, Northrup, Emily, Cuppen, Edwin, Hedrich, Hans J., Wedekind, Dirk |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066203/ https://www.ncbi.nlm.nih.gov/pubmed/21479269 http://dx.doi.org/10.1371/journal.pone.0015669 |
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