A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome. The LGI1 gene seems to have a role on the transmission of neuronal messages but the exact molecular me...

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Detalles Bibliográficos
Autores principales: Leonardi, Emanuela, Andreazza, Simonetta, Vanin, Stefano, Busolin, Giorgia, Nobile, Carlo, Tosatto, Silvio C. E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066209/
https://www.ncbi.nlm.nih.gov/pubmed/21479274
http://dx.doi.org/10.1371/journal.pone.0018142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066209/
https://www.ncbi.nlm.nih.gov/pubmed/21479274
http://dx.doi.org/10.1371/journal.pone.0018142

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