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A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins
Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome. The LGI1 gene seems to have a role on the transmission of neuronal messages but the exact molecular me...
Autores principales: | Leonardi, Emanuela, Andreazza, Simonetta, Vanin, Stefano, Busolin, Giorgia, Nobile, Carlo, Tosatto, Silvio C. E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066209/ https://www.ncbi.nlm.nih.gov/pubmed/21479274 http://dx.doi.org/10.1371/journal.pone.0018142 |
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