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Tuberous Sclerosis Complex-1 Deficiency Attenuates Diet-Induced Hepatic Lipid Accumulation

Non-alcoholic fatty liver disease (NAFLD) is causally linked to type 2 diabetes, insulin resistance and dyslipidemia. In a normal liver, insulin suppresses gluconeogenesis and promotes lipogenesis. In type 2 diabetes, the liver exhibits selective insulin resistance by failing to inhibit hepatic gluc...

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Detalles Bibliográficos
Autores principales: Kenerson, Heidi L., Yeh, Matthew M., Yeung, Raymond S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066210/
https://www.ncbi.nlm.nih.gov/pubmed/21479224
http://dx.doi.org/10.1371/journal.pone.0018075