IL-1α Mediated Chorioamnionitis Induces Depletion of FoxP3+ Cells and Ileal Inflammation in the Ovine Fetal Gut

BACKGROUND: Endotoxin induced chorioamnionitis increases IL-1 and provokes an inflammatory response in the fetal ileum that interferes with intestinal maturation. In the present study, we tested in an ovine chorioamnionitis model whether IL-1 is a major cytokine driving the inflammatory response in...

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Detalles Bibliográficos
Autores principales: Wolfs, Tim G. A. M., Kallapur, Suhas G., Polglase, Graeme R., Pillow, J. Jane, Nitsos, Ilias, Newnham, John P., Chougnet, Claire A., Kroon, Elke, Spierings, Julia, Willems, Coen H. M. P., Jobe, Alan H., Kramer, Boris W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066237/
https://www.ncbi.nlm.nih.gov/pubmed/21479249
http://dx.doi.org/10.1371/journal.pone.0018355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066237/
https://www.ncbi.nlm.nih.gov/pubmed/21479249
http://dx.doi.org/10.1371/journal.pone.0018355

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