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IL-1α Mediated Chorioamnionitis Induces Depletion of FoxP3+ Cells and Ileal Inflammation in the Ovine Fetal Gut
BACKGROUND: Endotoxin induced chorioamnionitis increases IL-1 and provokes an inflammatory response in the fetal ileum that interferes with intestinal maturation. In the present study, we tested in an ovine chorioamnionitis model whether IL-1 is a major cytokine driving the inflammatory response in...
Autores principales: | Wolfs, Tim G. A. M., Kallapur, Suhas G., Polglase, Graeme R., Pillow, J. Jane, Nitsos, Ilias, Newnham, John P., Chougnet, Claire A., Kroon, Elke, Spierings, Julia, Willems, Coen H. M. P., Jobe, Alan H., Kramer, Boris W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066237/ https://www.ncbi.nlm.nih.gov/pubmed/21479249 http://dx.doi.org/10.1371/journal.pone.0018355 |
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