Cargando…

Negative Regulator of MAP Kinase is Increased in Depression and Is Necessary and Sufficient for Expression of Depressive Behavior

Lifetime prevalence (~16%)1 and the economic burden ($100 billion annually)2,3 associated with major depressive disorder (MDD) make it one of the most common and debilitating neurobiological illnesses. To date, the exact cellular and molecular mechanisms underlying the pathophysiology of MDD have no...

Descripción completa

Detalles Bibliográficos
Autores principales: Duric, Vanja, Banasr, Mounira, Licznerski, Pawel, Schmidt, Heath D., Stockmeier, Craig A., Simen, Arthur A., Newton, Samuel S., Duman, Ronald S.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066515/
https://www.ncbi.nlm.nih.gov/pubmed/20953200
http://dx.doi.org/10.1038/nm.2219