Cargando…

Negative Regulator of MAP Kinase is Increased in Depression and Is Necessary and Sufficient for Expression of Depressive Behavior

Lifetime prevalence (~16%)1 and the economic burden ($100 billion annually)2,3 associated with major depressive disorder (MDD) make it one of the most common and debilitating neurobiological illnesses. To date, the exact cellular and molecular mechanisms underlying the pathophysiology of MDD have no...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duric, Vanja, Banasr, Mounira, Licznerski, Pawel, Schmidt, Heath D., Stockmeier, Craig A., Simen, Arthur A., Newton, Samuel S., Duman, Ronald S.
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066515/ https://www.ncbi.nlm.nih.gov/pubmed/20953200 http://dx.doi.org/10.1038/nm.2219

Ejemplares similares

Characterization of GABAergic Marker Expression in the Chronic Unpredictable Stress Model of Depression
por: Banasr, Mounira, et al.
Publicado: (2017)

Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress
por: Licznerski, Pawel, et al.
Publicado: (2015)

Decreased Expression of Synapse-Related Genes and Loss of Synapses in Major Depressive Disorder
por: Kang, H.J., et al.
Publicado: (2012)

Cariprazine Exhibits Anxiolytic and Dopamine D(3) Receptor-Dependent Antidepressant Effects in the Chronic Stress Model
por: Duric, Vanja, et al.
Publicado: (2017)

REDD1 is essential for stress-induced synaptic loss and depressive behavior
por: Ota, Kristie T., et al.
Publicado: (2014)

A Medial Prefrontal Cortex Cell Type Necessary and Sufficient for a Rapid Antidepressant Response
por: Hare, Brendan D., et al.
Publicado: (2019)

Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses
por: Fogaça, Manoela V., et al.
Publicado: (2020)

BDNF Release Is Required for the Behavioral Actions of Ketamine
por: Lepack, Ashley E., et al.
Publicado: (2014)

Necessary or Sufficient Condition for Gastroscopy
por: Chung, Min Suk
Publicado: (2019)

Neuronal function is necessary but not sufficient for consciousness: consciousness is necessary for will
por: Nussbaum, David, et al.
Publicado: (2012)

Abnormal expression of cortical cell cycle regulators underlying anxiety and depressive-like behavior in mice exposed to chronic stress
por: Mendes-Silva, Ana Paula, et al.
Publicado: (2022)

Cellular abnormalities in depression: evidence from postmortem brain tissue
por: Stockmeier, Craig A., et al.
Publicado: (2004)

Evidence-Based Health: Necessary But Not Sufficient
por: Herman, Elizabeth, et al.
Publicado: (2011)

A necessary and sufficient condition on diffeomorphisms
por: Li, W, et al.
Publicado: (1996)

Reversal of Antithrombotic Therapy: Is it Necessary and Sufficient?
por: Becker, Richard C.
Publicado: (2017)

Necessary but not sufficient: unique author identifiers
por: Harrison, Andrew Marc, et al.
Publicado: (2016)

Hedgehog signaling is necessary and sufficient to mediate craniofacial plasticity in teleosts
por: Navon, Dina, et al.
Publicado: (2020)

Prophylactic Efficacy of Riluzole against Anxiety- and Depressive-Like Behaviors in Two Rodent Stress Models
por: Bansal, Yashika, et al.
Publicado: (2023)

VEGF-A Is Necessary and Sufficient for Retinal Neuroprotection in Models of Experimental Glaucoma
por: Foxton, Richard H., et al.
Publicado: (2013)

Interaction of leukocyte integrins with ligand is necessary but not sufficient for function
Publicado: (1992)

IS A GRANDMAL SEIZURE NECESSARY AND SUFFICIENT FOR THE EFFICACY OF ECT?
por: Gangadhar, B.N., et al.
Publicado: (2000)

Necessary and sufficient conditions for minimality of linear dynamic systems
por: Scherer, R, et al.
Publicado: (1996)

A Necessary and Sufficient Criterion for the Separability of Quantum State
por: Li, Jun-Li, et al.
Publicado: (2018)

The necessary and sufficient mechanism of consciousness in a layered mind
por: Ruan, Zenan
Publicado: (2023)

S127. “HOW COULD THIS HAPPEN?”: PSYCHOSIS OR DEPRESSION AS A FACTOR IN DEATH BY SUICIDE
por: Overholser, James, et al.
Publicado: (2018)

Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior
por: Codeluppi, S.A., et al.
Publicado: (2023)

Interferon Regulatory Factor 6 is necessary but not sufficient for keratinocyte differentiation
por: Biggs, Leah C., et al.
Publicado: (2011)

Osteocalcin is necessary and sufficient to maintain muscle mass in older mice
por: Mera, Paula, et al.
Publicado: (2016)

Dopamine transients are sufficient and necessary for acquisition of model-based associations
por: Sharpe, Melissa J, et al.
Publicado: (2017)

Why Policy Changes May Be Necessary but Not Sufficient in Overcoming Disparities
por: Waterman, Amy D., et al.
Publicado: (2020)

Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient
por: Dal-Pra, Sophie, et al.
Publicado: (2019)

Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes
por: Chaurasia, Bhagirath, et al.
Publicado: (2020)

Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis
por: Droho, Steven, et al.
Publicado: (2021)

The Necessary and Sufficient Conditions When Global and Local Fidelities Are Equal
por: Kim, Seong-Kun, et al.
Publicado: (2023)

Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections
por: Duman, Ronald S.
Publicado: (2014)

Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression
por: Duman, Ronald S.
Publicado: (2009)

Neuroplasticity in cognitive and psychological mechanisms of depression: An integrative model
por: Price, Rebecca B., et al.
Publicado: (2019)

TRANCE Is Necessary and Sufficient for Osteoblast-mediated Activation of Bone Resorption in Osteoclasts
por: Fuller, Karen, et al.
Publicado: (1998)

IS A GRANDMAL SEIZURE NECESSARY AND SUFFICIENT FOR THE EFFICACY OF ELECTRO CONVULSIVE THERAPY?
por: Verghese, Abraham
Publicado: (2000)

Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation
por: Stocks, Blair T., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_574v05sh4f6cvj3sqn6iq5k20r