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Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery

Targeted PEGylated liposomes could increase the amount of drugs or radionuclides delivered to tumor cells. They show favorable stability and pharmacokinetics, but steric hindrance of the PEG chains can block the binding of the targeting moiety. Here, specific interactions between an antihapten antib...

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Detalles Bibliográficos
Autores principales: Botosoa, Eliot. P., Maillasson, Mike, Mougin-Degraef, Marie, Remaud-Le Saëc, Patricia, Gestin, Jean-François, Jacques, Yannick, Barbet, Jacques, Faivre-Chauvet, Alain
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066559/
https://www.ncbi.nlm.nih.gov/pubmed/21490749
http://dx.doi.org/10.1155/2011/368535