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Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery
Targeted PEGylated liposomes could increase the amount of drugs or radionuclides delivered to tumor cells. They show favorable stability and pharmacokinetics, but steric hindrance of the PEG chains can block the binding of the targeting moiety. Here, specific interactions between an antihapten antib...
Autores principales: | Botosoa, Eliot. P., Maillasson, Mike, Mougin-Degraef, Marie, Remaud-Le Saëc, Patricia, Gestin, Jean-François, Jacques, Yannick, Barbet, Jacques, Faivre-Chauvet, Alain |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066559/ https://www.ncbi.nlm.nih.gov/pubmed/21490749 http://dx.doi.org/10.1155/2011/368535 |
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