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New Concepts of Fluorescent Probes for Specific Detection of DNA Sequences: Bis-Modified Oligonucleotides in Excimer and Exciplex Detection

The detection of single base mismatches in DNA is important for diagnostics, treatment of genetic diseases, and identification of single nucleotide polymorphisms. Highly sensitive, specific assays are needed to investigate genetic samples from patients. The use of a simple fluorescent nucleoside ana...

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Detalles Bibliográficos
Autores principales: Gbaj, A, Bichenkova, EV, Walsh, L, Savage, HE, Sardarian, AR, Etchells, LL, Gulati, A, Hawisa, S, Douglas, KT
Formato: Texto
Lenguaje:English
Publicado: CoAction Publishing 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066750/
https://www.ncbi.nlm.nih.gov/pubmed/21483539
http://dx.doi.org/10.4176/090801