Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease

BACKGROUND: HIV preferentially infects CD4+ T cells, and the functional impairment and numerical decline of CD4+ and CD8+ T cells characterize HIV disease. The numerical decline of CD4+ and CD8+ T cells affects the optimal ratio between the two cell types necessary for immune regulation. Therefore,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jing Qin, Dwyer, Dominic E, Dyer, Wayne B, Yang, Yee Hwa, Wang, Bin, Saksena, Nitin K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068086/
https://www.ncbi.nlm.nih.gov/pubmed/21410942
http://dx.doi.org/10.1186/1742-4690-8-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068086/
https://www.ncbi.nlm.nih.gov/pubmed/21410942
http://dx.doi.org/10.1186/1742-4690-8-18

Ejemplares similares