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Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease

BACKGROUND: HIV preferentially infects CD4+ T cells, and the functional impairment and numerical decline of CD4+ and CD8+ T cells characterize HIV disease. The numerical decline of CD4+ and CD8+ T cells affects the optimal ratio between the two cell types necessary for immune regulation. Therefore,...

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Detalles Bibliográficos
Autores principales:	Wu, Jing Qin, Dwyer, Dominic E, Dyer, Wayne B, Yang, Yee Hwa, Wang, Bin, Saksena, Nitin K
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068086/ https://www.ncbi.nlm.nih.gov/pubmed/21410942 http://dx.doi.org/10.1186/1742-4690-8-18

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