T cell mediated cerebral hemorrhages and microhemorrhages during passive Aβ immunization in APPPS1 transgenic mice

BACKGROUND: Immunization against amyloid-β (Aβ), the peptide that accumulates in the form of senile plaques and in the cerebrovasculature in Alzheimer's disease (AD), causes a dramatic immune response that prevents plaque formation and clears accumulated Aβ in transgenic mice. In a clinical tri...

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Detalles Bibliográficos
Autores principales: Meyer-Luehmann, Melanie, Mora, J Rodrigo, Mielke, Matthew, Spires-Jones, Tara L, de Calignon, Alix, von Andrian, Ulrich H, Hyman, Bradley T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068114/
https://www.ncbi.nlm.nih.gov/pubmed/21388539
http://dx.doi.org/10.1186/1750-1326-6-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068114/
https://www.ncbi.nlm.nih.gov/pubmed/21388539
http://dx.doi.org/10.1186/1750-1326-6-22

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