Cargando…

The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells

BACKGROUND: Many cancer cells develop resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis, necessitating combination with chemotherapy, and normal cells manifest side effects due to the combined treatment regimen of TRAIL and chemotherapeutic drugs. A nove...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Hongyun, Qin, Yong, Li, Jianyong, Gong, Xingguo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068130/
https://www.ncbi.nlm.nih.gov/pubmed/21418589
http://dx.doi.org/10.1186/1741-7007-9-18