Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

BACKGROUND: Mutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-Gilford progeria syndrome and a group of laminopathies. Our understanding of how A-type lamins function in vivo during early vertebrate development through aging remains limit...

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Detalles Bibliográficos
Autores principales: Koshimizu, Eriko, Imamura, Shintaro, Qi, Jie, Toure, Jamal, Valdez, Delgado M., Carr, Christopher E., Hanai, Jun-ichi, Kishi, Shuji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068137/
https://www.ncbi.nlm.nih.gov/pubmed/21479207
http://dx.doi.org/10.1371/journal.pone.0017688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068137/
https://www.ncbi.nlm.nih.gov/pubmed/21479207
http://dx.doi.org/10.1371/journal.pone.0017688

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