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Activated Platelets in Carotid Artery Thrombosis in Mice Can Be Selectively Targeted with a Radiolabeled Single-Chain Antibody

BACKGROUND: Activated platelets can be found on the surface of inflamed, rupture-prone and ruptured plaques as well as in intravascular thrombosis. They are key players in thrombosis and atherosclerosis. In this study we describe the construction of a radiolabeled single-chain antibody targeting the...

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Detalles Bibliográficos
Autores principales: Heidt, Timo, Deininger, Friederike, Peter, Karlheinz, Goldschmidt, Jürgen, Pethe, Annette, Hagemeyer, Christoph E., Neudorfer, Irene, Zirlik, Andreas, Weber, Wolfgang A., Bode, Christoph, Meyer, Philipp T., Behe, Martin, von zur Mühlen, Constantin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068185/
https://www.ncbi.nlm.nih.gov/pubmed/21479193
http://dx.doi.org/10.1371/journal.pone.0018446