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Evidence for Enhanced Tissue Factor Expression in Age-related Macular Degeneration

Tissue factor (TF) is the primary initiator of blood coagulation. In addition to hemostasis, TF can initiate intracellular signaling and promote inflammation and angiogenesis, the key processes underlying the pathogenesis of age-related macular degeneration (AMD). AMD, the leading cause of irreversi...

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Detalles Bibliográficos
Autores principales: Cho, Youngeun, Cao, Xiaoguang, Shen, DeFen, Tuo, Jingsheng, Parver, Leonard M., Rickles, Frederick R., Chan, Chi-Chao
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068211/
https://www.ncbi.nlm.nih.gov/pubmed/21042291
http://dx.doi.org/10.1038/labinvest.2010.184