Trapping a translocating protein within the anthrax toxin channel: implications for the secondary structure of permeating proteins

Anthrax toxin consists of three proteins: lethal factor (LF), edema factor (EF), and protective antigen (PA). This last forms a heptameric channel, (PA(63))(7), in the host cell’s endosomal membrane, allowing the former two (which are enzymes) to be translocated into the cytosol. (PA(63))(7) incorpo...

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Detalles Bibliográficos
Autores principales: Basilio, Daniel, Jennings-Antipov, Laura D., Jakes, Karen S., Finkelstein, Alan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068283/
https://www.ncbi.nlm.nih.gov/pubmed/21402886
http://dx.doi.org/10.1085/jgp.201010578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068283/
https://www.ncbi.nlm.nih.gov/pubmed/21402886
http://dx.doi.org/10.1085/jgp.201010578

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