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Trapping a translocating protein within the anthrax toxin channel: implications for the secondary structure of permeating proteins
Anthrax toxin consists of three proteins: lethal factor (LF), edema factor (EF), and protective antigen (PA). This last forms a heptameric channel, (PA(63))(7), in the host cell’s endosomal membrane, allowing the former two (which are enzymes) to be translocated into the cytosol. (PA(63))(7) incorpo...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068283/ https://www.ncbi.nlm.nih.gov/pubmed/21402886 http://dx.doi.org/10.1085/jgp.201010578 |