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Pre-synaptic HCN1 channels regulate excitatory neurotransmission at select cortical synapses by altering Ca(V)3.2 Ca(2+) channel activity
The Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channels are subthreshold, voltage-gated ion channels that are highly expressed in hippocampal and cortical pyramidal cell dendrites, where they play an important role in regulating synaptic potential integration and plasticity. Here, we...
Autores principales: | Huang, Zhuo, Lujan, Rafael, Kadurin, Ivan, Uebele, Victor N., Renger, John J., Dolphin, Annette C., Shah, Mala M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068302/ https://www.ncbi.nlm.nih.gov/pubmed/21358644 http://dx.doi.org/10.1038/nn.2757 |
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