The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis

BACKGROUND: To investigate small-nucleolar RNAs (snoRNAs) as reference genes when measuring miRNA expression in tumour samples, given emerging evidence for their role in cancer. METHODS: Four snoRNAs, commonly used for normalisation, RNU44, RNU48, RNU43 and RNU6B, and miRNA known to be associated wi...

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Detalles Bibliográficos
Autores principales: Gee, H E, Buffa, F M, Camps, C, Ramachandran, A, Leek, R, Taylor, M, Patil, M, Sheldon, H, Betts, G, Homer, J, West, C, Ragoussis, J, Harris, A L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068486/
https://www.ncbi.nlm.nih.gov/pubmed/21407217
http://dx.doi.org/10.1038/sj.bjc.6606076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068486/
https://www.ncbi.nlm.nih.gov/pubmed/21407217
http://dx.doi.org/10.1038/sj.bjc.6606076

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