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A chemically modified antibody mediates complete eradication of tumours by selective disruption of tumour blood vessels

BACKGROUND: The possibility of eradicating cancer by selective destruction of tumour blood vessels may represent an attractive therapeutic avenue, but most pharmaceutical agents investigated so far did not achieve complete cures and are not completely specific. Antibody conjugates now allow us to ev...

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Detalles Bibliográficos
Autores principales: Palumbo, A, Hauler, F, Dziunycz, P, Schwager, K, Soltermann, A, Pretto, F, Alonso, C, Hofbauer, G F, Boyle, R W, Neri, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068510/
https://www.ncbi.nlm.nih.gov/pubmed/21386847
http://dx.doi.org/10.1038/bjc.2011.78