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Overexpression of TUF1 restores respiratory growth and fluconazole sensitivity to a Cryptococcus neoformans vad1Δ mutant

The yeast-like fungus Cryptococcus neoformans favours respiration as a mechanism of energy production, and thus depends heavily on mitochondrial function. Previous studies of a C. neoformans vad1Δ mutant revealed reduced expression of the mitochondrial elongation factor TUF1 and defects in glycerol...

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Detalles Bibliográficos
Autores principales: Panepinto, John C., Misener, Amanda L., Oliver, Brian G., Hu, Guowu, Park, Yoon Dong, Shin, Soowan, White, Theodore C., Williamson, Peter R.
Formato: Texto
Lenguaje:English
Publicado: Microbiology Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068674/
https://www.ncbi.nlm.nih.gov/pubmed/20430817
http://dx.doi.org/10.1099/mic.0.035923-0