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Overexpression of TUF1 restores respiratory growth and fluconazole sensitivity to a Cryptococcus neoformans vad1Δ mutant
The yeast-like fungus Cryptococcus neoformans favours respiration as a mechanism of energy production, and thus depends heavily on mitochondrial function. Previous studies of a C. neoformans vad1Δ mutant revealed reduced expression of the mitochondrial elongation factor TUF1 and defects in glycerol...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Microbiology Society
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068674/ https://www.ncbi.nlm.nih.gov/pubmed/20430817 http://dx.doi.org/10.1099/mic.0.035923-0 |