Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent infection: implications for immune modulation

Mycobacterium tuberculosis serine/threonine protein kinases (STPKs) are key regulators of growth and metabolism; however, evidence for their roles in virulence is limited. In a preliminary screen based on comparative expression between strains H37Rv and H37Ra, six STPK genes, pknD, pknG, pknH, pknJ,...

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Detalles Bibliográficos
Autores principales: Malhotra, Vandana, Arteaga-Cortés, Lourdes T., Clay, Gwendolyn, Clark-Curtiss, Josephine E.
Formato: Texto
Lenguaje:English
Publicado: Microbiology Society 2010
Materias:
Microbial Pathogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068690/
https://www.ncbi.nlm.nih.gov/pubmed/20522497
http://dx.doi.org/10.1099/mic.0.040675-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068690/
https://www.ncbi.nlm.nih.gov/pubmed/20522497
http://dx.doi.org/10.1099/mic.0.040675-0

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