Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the Chemosensitivity of Tumour Cells

Using transcriptomic and metabolomic measurements from the NCI60 cell line panel, together with a novel approach to integration of molecular profile data, we show that the biochemical pathways associated with tumour cell chemosensitivity to platinum-based drugs are highly coincident, i.e. they descr...

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Detalles Bibliográficos
Autores principales: Cavill, Rachel, Kamburov, Atanas, Ellis, James K., Athersuch, Toby J., Blagrove, Marcus S. C., Herwig, Ralf, Ebbels, Timothy M. D., Keun, Hector C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068923/
https://www.ncbi.nlm.nih.gov/pubmed/21483477
http://dx.doi.org/10.1371/journal.pcbi.1001113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068923/
https://www.ncbi.nlm.nih.gov/pubmed/21483477
http://dx.doi.org/10.1371/journal.pcbi.1001113

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