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ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells

BACKGROUND: Adult T-cell leukemia (ATL) is an aggressive malignancy of CD4(+ )T-cells caused by human T-cell leukemia virus type 1 (HTLV-1). The HTLV-1 bZIP factor (HBZ) gene, which is encoded by the minus strand of the viral genome, is expressed as an antisense transcript in all ATL cases. By using...

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Detalles Bibliográficos
Autores principales: Hagiya, Keita, Yasunaga, Jun-ichirou, Satou, Yorifumi, Ohshima, Koichi, Matsuoka, Masao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068935/
https://www.ncbi.nlm.nih.gov/pubmed/21414204
http://dx.doi.org/10.1186/1742-4690-8-19