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Position and sequence conservation in Amniota of polymorphic enhancer HS1.2 within the palindrome of IgH 3'Regulatory Region

BACKGROUND: The Immunoglobulin heavy chain (IgH) 3' Regulatory Region (3'RR), located at the 3' of the constant alpha gene, plays a crucial role in immunoglobulin production. In humans, there are 2 copies of the 3'RR, each composed of 4 main elements: 3 enhancers and a 20 bp tand...

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Detalles Bibliográficos
Autores principales: D'Addabbo, Pietro, Scascitelli, Moira, Giambra, Vincenzo, Rocchi, Mariano, Frezza, Domenico
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068965/
https://www.ncbi.nlm.nih.gov/pubmed/21406099
http://dx.doi.org/10.1186/1471-2148-11-71