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Class V β-tubulin alters dynamic instability and stimulates microtubule detachment from centrosomes

A multigene family produces tubulin isotypes that are expressed in a tissue-specific manner, but the role of these isotypes in microtubule assembly and function is unclear. Recently we showed that overexpression or depletion of β5-tubulin, a minor isotype with wide tissue distribution, inhibits cell...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Rajat, Yang, Hailing, Cabral, Fernando
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069006/
https://www.ncbi.nlm.nih.gov/pubmed/21289088
http://dx.doi.org/10.1091/mbc.E10-10-0822