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Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage

Coilin is a nuclear phosphoprotein that concentrates within Cajal bodies (CBs) and impacts small nuclear ribonucleoprotein (snRNP) biogenesis. Cisplatin and γ-irradiation, which cause distinct types of DNA damage, both trigger the nucleolar accumulation of coilin, and this temporally coincides with...

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Detalles Bibliográficos
Autores principales: Gilder, Andrew S., Do, Phi M., Carrero, Zunamys I, Cosman, Angela M., Broome, Hanna J., Velma, Venkatramreddy, Martinez, Luis A., Hebert, Michael D.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069010/
https://www.ncbi.nlm.nih.gov/pubmed/21289084
http://dx.doi.org/10.1091/mbc.E10-08-0731