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Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage
Coilin is a nuclear phosphoprotein that concentrates within Cajal bodies (CBs) and impacts small nuclear ribonucleoprotein (snRNP) biogenesis. Cisplatin and γ-irradiation, which cause distinct types of DNA damage, both trigger the nucleolar accumulation of coilin, and this temporally coincides with...
Autores principales: | Gilder, Andrew S., Do, Phi M., Carrero, Zunamys I, Cosman, Angela M., Broome, Hanna J., Velma, Venkatramreddy, Martinez, Luis A., Hebert, Michael D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069010/ https://www.ncbi.nlm.nih.gov/pubmed/21289084 http://dx.doi.org/10.1091/mbc.E10-08-0731 |
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