NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels

Short-chain quinones are described as potent antioxidants and in the case of idebenone have already been under clinical investigation for the treatment of neuromuscular disorders. Due to their analogy to coenzyme Q(10) (CoQ(10)), a long-chain quinone, they are widely regarded as a substitute for CoQ...

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Detalles Bibliográficos
Autores principales: Haefeli, Roman H., Erb, Michael, Gemperli, Anja C., Robay, Dimitri, Courdier Fruh, Isabelle, Anklin, Corinne, Dallmann, Robert, Gueven, Nuri
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069029/
https://www.ncbi.nlm.nih.gov/pubmed/21483849
http://dx.doi.org/10.1371/journal.pone.0017963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069029/
https://www.ncbi.nlm.nih.gov/pubmed/21483849
http://dx.doi.org/10.1371/journal.pone.0017963

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