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NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels
Short-chain quinones are described as potent antioxidants and in the case of idebenone have already been under clinical investigation for the treatment of neuromuscular disorders. Due to their analogy to coenzyme Q(10) (CoQ(10)), a long-chain quinone, they are widely regarded as a substitute for CoQ...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069029/ https://www.ncbi.nlm.nih.gov/pubmed/21483849 http://dx.doi.org/10.1371/journal.pone.0017963 |