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Mycobacterium tuberculosis Induces an Atypical Cell Death Mode to Escape from Infected Macrophages

BACKGROUND: Macrophage cell death following infection with Mycobacterium tuberculosis plays a central role in tuberculosis disease pathogenesis. Certain attenuated strains induce extrinsic apoptosis of infected macrophages but virulent strains of M. tuberculosis suppress this host response. We previ...

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Detalles Bibliográficos
Autores principales: Lee, Jinhee, Repasy, Teresa, Papavinasasundaram, Kadamba, Sassetti, Christopher, Kornfeld, Hardy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069075/
https://www.ncbi.nlm.nih.gov/pubmed/21483832
http://dx.doi.org/10.1371/journal.pone.0018367