COMMD1-Mediated Ubiquitination Regulates CFTR Trafficking

The CFTR (cystic fibrosis transmembrane conductance regulator) protein is a large polytopic protein whose biogenesis is inefficient. To better understand the regulation of CFTR processing and trafficking, we conducted a genetic screen that identified COMMD1 as a new CFTR partner. COMMD1 is a protein...

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Detalles Bibliográficos
Autores principales: Drévillon, Loïc, Tanguy, Gaëlle, Hinzpeter, Alexandre, Arous, Nicole, de Becdelièvre, Alix, Aissat, Abdel, Tarze, Agathe, Goossens, Michel, Fanen, Pascale
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069076/
https://www.ncbi.nlm.nih.gov/pubmed/21483833
http://dx.doi.org/10.1371/journal.pone.0018334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069076/
https://www.ncbi.nlm.nih.gov/pubmed/21483833
http://dx.doi.org/10.1371/journal.pone.0018334

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